Postoffer Pre-Placement Screening for Carpal Tunnel Syndrome in Newly Hired Manufacturing Workers

OBJECTIVE: We determined the predictive validity of a post-offer pre-placement (POPP) screen using nerve conduction velocity studies (NCV) to identify future cases of carpal tunnel syndrome (CTS). METHODS: A cohort of 1648 newly hired manufacturing production workers underwent baseline NCS, and were followed for 5 years. RESULTS: There was no association between abnormal POPP NCV results and incident CTS. Varying NCV diagnostic cut-offs did not improve predictive validity. Workers in jobs with high hand/wrist exposure showed greater risk of CTS than those in low exposed jobs (Relative Risk 2.82; 95% CI 1.52, 5.22). CONCLUSIONS: POPP screening seems ineffective as a preventive strategy for CTS

Functional Measures Developed for Clinical Populations Identified Impairment Among Active Workers with Upper Extremity Disorders

PURPOSE: Few studies have explored measures of function across a range of health outcomes in a general working population. Using four upper extremity (UE) case definitions from the scientific literature, we described the performance of functional measures of work, activities of daily living, and overall health. METHODS: A sample of 573 workers completed several functional measures: modified recall versions of the QuickDASH, Levine Functional Status Scale (FSS), DASH Work module (DASH-W), and standard SF-8 physical component score. We determined case status based on four UE case definitions: 1) UE symptoms, 2) UE musculoskeletal disorders (MSD), 3) carpal tunnel syndrome (CTS), and 4) work limitations due to UE symptoms. We calculated effect sizes for each case definition to show the magnitude of the differences that were detected between cases and non-cases for each case definition on each functional measure. Sensitivity and specificity analyses showed how well each measure identified functional impairments across the UE case definitions. RESULTS: All measures discriminated between cases and non-cases for each case definition with the largest effect sizes for CTS and work limitations, particularly for the modified FSS and DASH-W measures. Specificity was high and sensitivity was low for outcomes of UE symptoms and UE MSD in all measures. Sensitivity was high for CTS and work limitations. CONCLUSIONS: Functional measures developed specifically for use in clinical, treatment-seeking populations may identify mild levels of impairment in relatively healthy, active working populations, but measures performed better among workers with CTS or those reporting limitations at work

Responsiveness of a 1-year recall modified DASH Work module in active workers with upper extremity musculoskeletal symptoms

OBJECTIVES: To evaluate the responsiveness to change of a modified version of the Work module of the Disabilities of the Arm, Shoulder, and Hand (DASH-W) in a prospective, longitudinal cohort study of active workers. METHODS: We compared change on a 1-year recall modified DASH-W to change on work ability, work productivity, and symptom severity, according to predetermined hypotheses following the Consensus-based standards for the selection of health measurement instruments (COSMIN). We evaluated concordance in the direction of change, and magnitude of change using Spearman rank correlations, effect sizes (ES), standardized response means (SRM), and area under the receiver operating characteristic curves (AUC). RESULTS: In a sample of 551 workers, change in 1-year recall modified DASH-W scores showed moderate correlations with changes in work ability, work productivity, and symptom severity (r=0.47, 0.44, and 0.36, respectively). ES and SRM were moderate for 1-year recall modified DASH-W scores in workers whose work ability (ES=−0.58, SRM=−0.52) and work productivity improved (ES=−0.59, SRM=−0.56), and larger for workers whose work ability (ES=1.24, SRM=0.68) and work productivity worsened (ES=1.02, SRM=0.61). ES and SRM were small for 1-year recall modified DASH-W scores of workers whose symptom severity improved (−0.32 and −0.29, respectively). Responsiveness of the 1-year recall modified DASH-W was moderate for those whose symptom severity worsened (ES=0.77, SRM=0.50). AUC met responsiveness criteria for work ability and work productivity. CONCLUSIONS: The 1-year recall modified DASH-W is responsive to changes in work ability and work productivity in active workers with upper extremity symptoms

Outcomes of single port robotic sacrocolpopexy compared with multi-port approaches

Importance: Scientific literature currently lacks data on surgical outcomes of single-port robotic sacrocolpopexy compared with traditional multi-port approaches. Objectives: To evaluate feasibility and surgical outcomes for the single-port robotic approach to sacrocolpopexy when compared with traditional multi-port approaches. Study design: Retrospective chart review of fifty patients who underwent minimally invasive sacrocolpopexy with a single urogynecologist between 2018 and 2021 ​at an academic tertiary care hospital. Patients were divided into three cohorts: laparoscopic multi-port (LMP), robotic multi-port (RMP), and robotic single-port (RSP). Outcome measures were operative time, number of adverse events, and severity of adverse events by Clavien-Dindo. Results: All patients underwent at least one concomitant procedure; however, LMP had more concomitant procedures compared to RMP and RSP (p ​< ​0.001). RMP had higher incidence of prior hysterectomy (p ​< ​0.001) and prior vaginal surgery (p ​= ​0.002) compared to LMP and RSP. There were no significant differences in age, BMI, ethnicity/race, pre-operative POPQ stage, number of prior laparoscopies/laparotomies, or prior hernia repair. Linear and Poisson regression models were used to assess between-group differences in the outcome measures while adjusting for confounders. LMP had significantly higher adverse event severity than RSP (RR ​= ​2.23, p ​= ​0.044). 62.5% of the RSP group had no adverse events. No other statistically significant differences were observed. Conclusion: This retrospective study demonstrates feasibility and safety of the single-port robotic approach for sacrocolpopexy when compared with traditional multi-port approaches. Larger, prospective studies are indicated to better understand post-operative outcomes

The CONSTANCES job exposure matrix based on self-reported exposure to physical risk factors: Development and evaluation

OBJECTIVES: Job exposure matrices (JEMs) can be constructed from expert-rated assessments, direct measurement and self-reports. This paper describes the construction of a general population JEM based on self-reported physical exposures, its ability to create homogeneous exposure groups (HEG) and the use of different exposure metrics to express job-level estimates. METHODS: The JEM was constructed from physical exposure data obtained from the Cohorte des consultants des Centres d\u27examens de santé (CONSTANCES). Using data from 35 526 eligible participants, the JEM consisted of 27 physical risk factors from 407 job codes. We determined whether the JEM created HEG by performing non-parametric multivariate analysis of variance (NPMANOVA). We compared three exposure metrics (mean, bias-corrected mean, median) by calculating within-job and between-job variances, and by residual plots between each metric and individual reported exposure. RESULTS: NPMANOVA showed significantly higher between-job than within-job variance among the 27 risk factors (F(253,21964)=61.33, p\u3c0.0001, r CONCLUSIONS: CONSTANCES JEM using self-reported data yielded HEGs, and can thus classify individual participants based on job title. The bias-corrected mean metric may better reflect the shape of the underlying exposure distribution. This JEM opens new possibilities for using unbiased exposure estimates to study the effects of workplace physical exposures on a variety of health conditions within a large general population study

Applying two general population job exposure matrices to predict incident carpal tunnel syndrome: A cross-national approach to improve estimation of workplace physical exposures

International audienc

Musculoskeletal symptoms associated with workplace physical exposures estimated by a job exposure matrix and by self-report

International audienceBackground A job-exposure matrix (JEM) is an efficient method to assign physical workplace exposures based on job titles. JEMs offer the possibility of linking work exposures to outcome data from national health registers that contain job titles. The French CONSTANCES JEM was constructed from self-reported physical work exposures of asymptomatic workers participating in a large general population study. We validated this general population JEM by testing its ability to demonstrate exposure-outcome associations for musculoskeletal disorders (MSD) symptoms. Methods The CONSTANCES JEM was evaluated by assigning exposure estimates to a validation sample of new participants in the CONSTANCES study (final n = 38 730). We used weighted Kappas to compare the level of agreement between JEM-assigned and self-reported exposures across job codes for each of the 27 physical exposure variables. We computed prevalence ratios and 95% confidence intervals using Poisson regression models adjusted for age and sex for pain at six body locations associated with work exposures estimated via individual self-report and by the JEM. Results Agreement between individual self-reported and JEM-assigned exposures ranged from kappa = 0.16 to 0.71; generally, the level of agreement was fair to good. We observed consistent and significant associations between pain and both self-reported and JEM-assigned exposures at all body locations. Conclusions The CONSTANCES JEM replicated known associations between physical risk factors and prevalent MSD symptoms. Physical exposure JEMs can reduce some types of information bias, and open new avenues of research in the prevention of MSDs and other health conditions related to workplace physical activities

Validity of a job-exposure matrix (JEM) score for carrying heavy loads compared to standardized self-reported evaluation in CONSTANCES cohort

International audienc